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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“It is found that bilateral subdiaphragmatic vagotomy and treatment of capsaicin , an excitotoxin for primary afferent neurons, could both block the anorectic effect of peripherally injected SCT.”
Vagal Afferent Mediates the Anorectic Effect of Peripheral Secretin“Vagal ligation but not perivagal capsaicin treatment reduced the inhibitory effect of secretin on bethanechol-stimulated contraction of isolated forestomach muscle strips, causing a right shift in the dose-response curve.”
“Recently, it was reported that secretin inhibited gastric emptying via a capsaicin (Cap)-sensitive vagal afferent pathway.”
“In conscious rats, the stimulation of sensory nerves by low dose of capsaicin given intraduodenally (0.25-0.5 mg/kg) reduced basal pancreatic secretion , whereas dose of 1 mg/kg increased this secretion.”
“ResultsIn conscious rats, CGRP given subcutaneously (5–10 μg/kg) and low doses of capsaicin given intraduodenally reduced basal pancreatic secretion.”
“Furthermore, perivagal and duodenojejunal mucosal application of capsaicin abolished the pancreatic secretory response to secretin at 5 pmol.kg-1.h-1.”
“Similarly, we also showed that gastroduodenal application of capsaicin for 30 min also markedly reduced gastric response to secretin.”
“Recently, it was reported that secretin inhibited gastric emptying via a capsaicin (Cap)-sensitive vagal afferent pathway.”
Secretin inhibits gastric acid secretion via a vagal afferent pathway in rats.
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