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Last Updated: 2 years ago

Possible Interaction: Capsaicin and Secretin

supplement:

Capsaicin

supplement:

Secretin

Research Papers that Mention the Interaction

It is found that bilateral subdiaphragmatic vagotomy and treatment of capsaicin , an excitotoxin for primary afferent neurons, could both block the anorectic effect of peripherally injected SCT.
PloS one  •  2013  |  View Paper
Vagal ligation but not perivagal capsaicin treatment reduced the inhibitory effect of secretin on bethanechol-stimulated contraction of isolated forestomach muscle strips, causing a right shift in the dose-response curve.
The American journal of physiology  •  1999  |  View Paper
Recently, it was reported that secretin inhibited gastric emptying via a capsaicin (Cap)-sensitive vagal afferent pathway.
The American journal of physiology  •  1998  |  View Paper
In conscious rats, the stimulation of sensory nerves by low dose of capsaicin given intraduodenally (0.25-0.5 mg/kg) reduced basal pancreatic secretion , whereas dose of 1 mg/kg increased this secretion.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society  •  1997  |  View Paper
ResultsIn conscious rats, CGRP given subcutaneously (5–10 μg/kg) and low doses of capsaicin given intraduodenally reduced basal pancreatic secretion.
International journal of pancreatology : official journal of the International Association of Pancreatology  •  1997  |  View Paper
Furthermore, perivagal and duodenojejunal mucosal application of capsaicin abolished the pancreatic secretory response to secretin at 5 pmol.kg-1.h-1.
The American journal of physiology  •  1995  |  View Paper
Similarly, we also showed that gastroduodenal application of capsaicin for 30 min also markedly reduced gastric response to secretin.
The American journal of physiology  •  1995  |  View Paper
Recently, it was reported that secretin inhibited gastric emptying via a capsaicin (Cap)-sensitive vagal afferent pathway.
American journal of physiology. Gastrointestinal and liver physiology  •  1998  |  View Paper