Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Capsaicin and Potassium

supplement:

Capsaicin

supplement:

Potassium

Research Papers that Mention the Interaction

The number and duration of cortical spreading depressions induced by potassium were significantly increased in animals injected with capsaicin in the bilateral whisker pad compared with animals injected in the bilateral plantar or in controls, while administration of a GABAA receptor agonist decreased these effects.
Neuroscience Research  •  2016  |  View Paper
In both species, administration of capsaicin (3·10−5 M) to the outer surface of the cell membrane reduced the amplitude and accelerated the inactivation of the fast inactivating potassium current.
Pflügers Archiv  •  2004  |  View Paper
Micromolar concentrations of capsaicin inhibited voltage-dependent sodium, calcium and potassium currents.
Neuroscience  •  2000  |  View Paper
2 Capsaicin caused a time‐dependent block of both the slow and fast components of the potassium current.
British journal of pharmacology  •  1996  |  View Paper
Resiniferatoxin, capsaicin , calcitonin gene-related peptide and neurokinin A all evoked a sustained, concentration-dependent vasodilatation of potassium (60 mM)-precontracted arteries.
Acta physiologica Scandinavica  •  1991  |  View Paper
Capsaicin (1 microM) produced a similar effect, and a previous exposure to capsaicin prevented the effect of potassium.
Neuroscience  •  1990  |  View Paper
Capsaicin also induced a long-lasting relaxation of potassium and PGF2 alpha-precontracted coronary arteries.
European journal of pharmacology  •  1987  |  View Paper
CAP attenuated the outward membrane currents with decreasing potency in the sequence of the transient potassium (IA) voltage-dependent potassium (IK), Ca-dependent potassium (IC) and leakage currents (IL).
Acta physiologica Hungarica  •  1987  |  View Paper
We suggest that the acute action of CAP coupled with a series of events in the neuronal membrane can modify the conductance via electrically excitable calcium, potassium and sodium channels differentially.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology  •  1986  |  View Paper
Incubation with potassium (25-100 mM) produced a dose-related increase in basal CGRP-LI in the supernatant of dorsal slices which was calcium dependent and release was also evoked by incubation with capsaicin (10 microM).
Neuroscience Letters  •  1994  |  View Paper