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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Capsaicin
drug:
Phenoxybenzamine
Research Papers that Mention the Interaction
“When applied after capsaicin, phenoxybenzamine inhibited thermal hyperalgesia at normal ambient temperatures, and during body warming and cooling.”
“When applied before capsaicin, phenoxybenzamine increased thermal hyperalgesia at normal ambient temperatures and during body warming.”
The effect of sympathetic activity on thermal hyperalgesia in capsaicin‐treated skin during body cooling and warming“However, iontophoresis of phenoxybenzamine before the capsaicin treatment was ineffective.”
“The contractile response to capsaicin or neurokinin A of the rat isolated bladder were significantly reduced by incubation with phenoxybenzamine at a concentration reported to produce a selective alkylation of neurokinin-2 receptors, while the response to substance P or KCl was unaffected.”
Tachykinin-like immunoreactivity in the mammalian urinary bladder: Correlation with the functions of the capsaicin-sensitive sensory nerves
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