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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Capsaicin and Ondansetron

supplement:

Capsaicin

Research Papers that Mention the Interaction

Significant, dose-dependent analgesic effects were produced by 100 microg and 250 microg doses of ondansetron ; these doses also reduced mechanical hyperalgesia produced by capsaicin.
Topical application of the 5-HT3 receptor antagonist ondansetron (50-250 microg) delivered in a pluronic lecithin organogel vehicle (PLO, 0.5 ml) produced dose-dependent attenuation of nociceptive and inflammatory effects of intradermally injected capsaicin (10 microg/10 microl) in humans.
European journal of pharmacology  •  1998  |  View Paper