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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Capsaicin and Nitroglycerin

supplement:

Capsaicin

Research Papers that Mention the Interaction

The addition of GTN to capsaicin cream significantly reduces the thermal allodynia associated with the application of capsaicin cream alone.
The thermal allodynia caused by the topical application of capsaicin was significantly reduced by the addition of GTN.
Neuroscience Letters  •  2002  |  View Paper
However, the elevated level of CGRP-LI by nitroglycerin was abolished by pretreatment with capsaicin.
Acta pharmacologica Sinica  •  2001  |  View Paper
Intradermal injection of capsaicin in the periorbital area increased c-fos expression in nucleus trigeminalis caudalis; this was significantly potentiated by glyceryl trinitrate.
Cephalalgia : an international journal of headache  •  2001  |  View Paper
Pretreatment with capsaicin , which specifically depletes the transmitter content of sensory nerves, also abolished the protection by nitroglycerin.
European journal of pharmacology  •  2001  |  View Paper
The effects of nitroglycerin were significantly attenuated by methylene blue, an inhibitor of guanylate cyclase, or by pretreatment with capsaicin (50 mg x kg(-1), s.c.),
Life sciences  •  2001  |  View Paper