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Last Updated: 2 months ago

Possible Interaction: Capsaicin and Nitric Oxide

supplement:

Capsaicin

Research Papers that Mention the Interaction

Conversely, when on capsaicin, NO significantly increased at 6 hours.
Journal of cardiovascular pharmacology  •  2004  |  View Paper
It is concluded that nitric oxide , possibly of sensory origin, is involved in the relaxant action of capsaicin in the circular muscle of the mouse and human intestine.
Life sciences  •  2005  |  View Paper
Capsaicin potently inhibits tone and movements of human intestinal preparations, an effect mediated by nitric oxide ( NO ) and/or vasoactive intestinal polypeptide.
European journal of pharmacology  •  2004  |  View Paper
Significant increase in NO release was observed when cells were incubated with CEX (100 microg/mL) and CAP (25 microM) and this effect was inhibited by CZP only in CAP treatment group.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet  •  2010  |  View Paper
Capsaicin decreased MDA (-45.5-76.1%), ET-1 (-19.6-51.6%), and average gray value (AGV) of eNOS (-10.9-48.8%), and increased SOD activity (+31.7-76.1%), NO (+11.2-36.8%), and AGV of iNOS (+6.8-+93.0%) (all P < 0.05).
Chemico-biological interactions  •  2019  |  View Paper
Phospho-eNOS levels were augmented, and NO production increased following the administration of capsaicin.
Journal of diabetes and its complications  •  2015  |  View Paper
CAP may lead to release of NO either directly from nerves or indirectly by evoking release from other cells via the action of neuropeptides that are released from afferent terminals and are involved in regulating female reproductive function.
Biotechnic & histochemistry : official publication of the Biological Stain Commission  •  2012  |  View Paper
Using 4,5-diaminofluorescein diacetate for nitric oxide (NO) imaging, we found that capsaicin also increased the production of NO in retinal blood vessels.
Cellular and Molecular Neurobiology  •  2012  |  View Paper
Serum nitric oxide showed marked increase after LPS injection, but was markedly decreased after capsaicin (1,500 μg/kg, i.p.).
Inflammopharmacology  •  2011  |  View Paper
In contrast, production of nitric oxide , which has the ability to reduce MHC class II expression, was not enhanced but rather suppressed by capsaicin treatment in IFN-gamma-stimulated macrophages.
International immunopharmacology  •  2010  |  View Paper
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