Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Capsaicin and Nicotine



Research Papers that Mention the Interaction

We hypothesized that withdrawal from and administration of nicotine in smoking subjects would modulate their anxiety levels, urge-to-cough and cough motor response to capsaicin stimulation.
Pulmonary pharmacology & therapeutics  •  2009  |  View Paper
Furthermore, nicotine evoked a significantly weaker sensation on the side of the tongue pretreated with capsaicin (cross-desensitization).
Chemical senses  •  1997  |  View Paper
capsaicin … nicotine ; 2) when the central end of the left cardiac sympathetic nerve was electrically stimulated, both the pressor and the RSNA responses to chemoreflex activation …) bilateral microinjection of losartan (250 pmol) into the nucleus tractus solitarii (NTS) completely abolished the enhanced chemoreceptor reflex by epicardial application of capsaicin.
Journal of applied physiology  •  2007  |  View Paper
The response to nicotine was also reduced following local pretreatment with capsaicin , while the response to systemic pretreatment with capsaicin was only slightly affected.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
Also, neonatal treatment with capsaicin , a procedure that is associated with a selective degeneration of primary sensory C-fibre afferents, clearly antagonized the effect of nicotine on LC neurons.
Psychopharmacology  •  2004  |  View Paper
The responses to nicotine were of short duration and blocked in preparations pre‐treated for 10 min with capsaicin (1 μM) and are therefore probably a consequence of the stimulation of trigeminal C fibre terminals.
British journal of pharmacology  •  1999  |  View Paper
The release of CGRP evoked by capsaicin was also reduced after nicotine and cytisine desensitization.
Journal of applied physiology  •  1994  |  View Paper
The relaxation produced by nicotine was attenuated in the presence of capsaicin (3 x 10(-7) M) to desensitize sensory nerves.
The Journal of pharmacology and experimental therapeutics  •  1993  |  View Paper
Pretreatment with 3 mM capsaicin applied locally to the nasal mucosa abolished or reduced the vasodilation in response to capsaicin, nicotine , and ammonia vapor but not to light mechanical or electrical stimulation of the nasal mucosa.
The American journal of physiology  •  1993  |  View Paper
Perfusion of control rat adrenal glands with capsaicin did not evoke CA secretion, but did increase CA secretion in response to perfusion with nicotine.
European journal of pharmacology  •  1990  |  View Paper
Show More