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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Capsaicin
drug:
Neuropeptide Y
Research Papers that Mention the Interaction
“Pretreatment of the nasal mucosa with exogenous NPY reduces both secretagogue and vasodilator responses to subsequent application of capsaicin.”
“Subjective nasal obstruction, local discomfort, nasal secretions and NAR increase evoked by capsaicin were markedly reduced by NPY pretreatment (P < 0.05) when compared to saline or oxymetazoline.”
Intranasal administration of neuropeptide Y in man: systemic absorption and functional effects“Pre-treatment with exogenous NPY markedly reduced nasal airway obstruction and rhinorrhea induced by the irritant capsaicin in control subjects.”
“Dorsal root immersion in capsaicin , but not its electrical stimulation, also induced NPY release.”
Neuropeptide Y release in the rat spinal cord measured with Y1 receptor internalization is increased after nerve injury“Release of endogenous CGRP by capsaicin significantly reduced the basal overflow of NA, ir-NPY , and the electrically evoked sympathetic transmitter release.”
“These results suggest that capsaicin influence neuropeptides such as orexigenic NPY and anorexigenic CCK related to control food intake.”
“3 NPY also significantly decreased plasma protein extravasation induced by capsaicin (1 μmol kg−1) but not by substance P (1 nmol kg−1).”
“ NPY (10−8m) completely inhibited the effects of acetylcholine and capsaicin on the Kf,c, without preventing the effects of substance P and 5‐HT.”
“Failure of NPY to modulate responses activated by capsaicin provides further evidence for the existence of two independent modes of activation of the ‘efferent’ function of capsaicin‐sensitive sensory nerves.”
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