Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Capsaicin and Minocycline

supplement:

Capsaicin

Research Papers that Mention the Interaction

Minocycline tended to reduce pre-capsaicin injection values of hyperalgesia in the affected leg by 28% (95% CI 0% to 56%).
PloS one  •  2012  |  View Paper
Inhibition of neurogenic inflammation by minocycline is suggested to be associated with its inhibitory effect on SGCs that are possibly activated following capsaicin injection.
Neuroscience Letters  •  2010  |  View Paper
Measurement of tumor necrosis factor α (TNF‐α) and its receptor, TNF‐α receptor 1 (TNFR1), showed that minocycline mainly blocked the up‐regulation of TNF‐α in SGCs and TNFR1s in neurons following capsaicin injection.
Clinical and experimental pharmacology & physiology  •  2015  |  View Paper