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Last Updated: 2 years ago

Possible Interaction: Capsaicin and Methysergide

supplement:

Capsaicin

Research Papers that Mention the Interaction

Blockade of 5-hydroxytryptamine receptors with methysergide led to a reduction of the permeability response in the oesophagus and in the urinary bladder, leaving responses in other organs unchanged.3.Pretreatment of neonatal rats with capsaicin almost abolished the 48/80 response in all organs except in the duodenum.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
In vivo pretreatment with compound 48/80 significantly reduced the in vitro contractions to neurokinin A. Contractions to capsaicin were inhibited by methysergide and the tachykinin NK1 receptor antagonist (+/-)-RP67580 ((3alphaR,7alphaR)-(7,7-diphenyl-2-(1-imino-2-(2-methoxyp henylethyl)-perhydraisoinotol-4-one))).
European journal of pharmacology  •  1997  |  View Paper