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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Capsaicin
drug:
Methacholine
Research Papers that Mention the Interaction
“These results confirm the decreased responses to repeated inhalation of methacholine (methacholine tachyphylaxis) in normal subjects and indicate that capsaicin inhalation reduces the methacholine tachyphylaxis.”
Effect of capsaicin inhalation on methacholine responsiveness in normal subjects“Blockade of neuromuscular transmission with botulinum neurotoxin A (1 U, 3 days), micropipette application of calcitonin gene-related peptide (CGRP) receptor … microM) 300 microm upstream from the methacholine application site, and denervation of the CGRP sensory nerve by 2 days of capsaicin treatment … to methacholine but did … dilatory response.”
Remote arteriolar dilations caused by methacholine: a role for CGRP sensory nerves?“ Capsaicin (100 microM) elicited relaxation in TSM contracted with methacholine.”
“ Capsaicin concentration producing coughs negatively correlated with methacholine PC20 (4 mg mL−1, p = 0.037), (16 mg mL−1, p = 0.069) and (20 mg mL−1, p = 0.045).”
Impact of capsaicin concentration evoking coughs on clinical variables in patients with asthma“ Capsaicin (100 μM) elicited relaxation in TSM contracted with methacholine.”
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