Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Capsaicin and Isoflavones





Research Papers that Mention the Interaction

Dermal levels of IGF-I were significantly higher in WT mice administered capsaicin and isoflavone for 4 wks than in those administered capsaicin alone for 4 wks (p < 0.01) and in those administered neither of them (p < 0.01).
Plasma levels of IGF-I were significantly increased from baseline levels in 31 volunteers with alopecia at 5 months after oral administration of capsaicin (6 mg/day) and isoflavone (75 mg/day) (p < 0.01), while they were not increased in 17 volunteers with alopecia administered placebo.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society  •  2007  |  View Paper
In contrast, systolic and diastolic BP was significantly reduced in hypertensive volunteers after administration of capsaicin and isoflavone.
Serum levels of IGF-I significantly increased in both normotensive and hypertensive volunteers after administration of capsaicin and isoflavone.
Bioscience, biotechnology, and biochemistry  •  2009  |  View Paper
CBTE displayed an affinity for estrogen receptor (ER)α, with an IC50 value of 74.8 µg/mL. … of CBTE might be mediated by the ERs, since a similar effect induced by orally administered soy isoflavone , a mixture of ERs ligands, has … reported to be synergistically potentiated by capsaicin.
Bioscience, biotechnology, and biochemistry  •  2013  |  View Paper