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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Finally, exposure of monolayers to capsaicin augmented the paracellular passage of both charged and uncharged compounds, as well as of insulin , indicating that capsaicin can be employed to modulate epithelial permeability.”
The Reversible Increase in Tight Junction Permeability Induced by Capsaicin Is Mediated via Cofilin-Actin Cytoskeletal Dynamics and Decreased Level of Occludin“Intraportal administration of L‐NAME (10 mg kg−1) decreased, whereas capsaicin (0.3 mg kg−1 min−1) increased insulin sensitivity.”
“ CAP administration markedly improved glucose tolerance and insulin sensitivity through decreasing gluconeogenesis and increasing glycogen synthesis in the liver.”
Capsaicin Improves Glucose Tolerance and Insulin Sensitivity Through Modulation of the Gut Microbiota-Bile Acid-FXR Axis in Type 2 Diabetic db/db Mice.“Dietary capsaicin lowered fasting glucose, insulin , leptin levels, and markedly reduced the impairment of glucose tolerance in obese mice.”
“ Capsaicin treatment also increased the levels of circulating glucose and triglycerides and negated the actions of insulin on these and free fatty acids and ketone bodies.”
“These results indicate that CAP rats have increased insulin sensitivity during hyperglycemic episodes, and lower plasma levels of corticosterone in CAP rats relative to VEH rats could underlie this effect.”
“Neonatal treatment with capsaicin decreased the hypoglycemic effect of insulin but had no effect on hyperglycemia following glucose doses, but decreased FFA levels.”
“These studies, showed that capsaicin stimulation of insulin intact rats decreased the hypoglycemic action of insulin , increased hyperglycemia following glucose dosage, increased FFA levels, and prevented the FFA-lowering effect of insulin.”
“The … that capsaicin interfered only with … adrenal effect of insulin suggests the involvement of afferent C-fibres in this insulin effect.6.Injection into the hepatic portal vein of a …-fibre stimulating dose of capsaicin increased arterial glucose concentrations in vehicle-pretreated rats but not in capsaicin-pretreated rats.”
“Coapplication of insulin (10 µm) with capsaicin , however, potentiated the 50 and 100 nm capsaicin‐evoked staining.”
“Neonatal capsaicin pre-treatment decreased the hypoglycaemic response effect of insulin and the FFA level.”
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