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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Capsaicin and Imiquimod



Research Papers that Mention the Interaction

CONCLUSION: Epicutaneous delivery of capsaicin on imiquimod-treated murine skin could significantly decrease expression of multiple inflammatory cytokines and the severity of prototypic change of psoriasiform inflammation.
The results showed that capsaicin administration obstructed the activation of IL-23/IL-17 pathway induced by imiquimod , presenting with significantly reduced psoriasiform dermatitis both in gross appearance and microscopic features.
Tissue gene expression of psoriatic core cytokines induced by imiquimod (including IL-23, IL-17A, IL-22, TNF-α, and IL-6) were greatly decreased by capsaicin application.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2021  |  View Paper