Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Capsaicin and Glutathione

supplement:

Capsaicin

supplement:

Glutathione

Research Papers that Mention the Interaction

A dose dependent significant increase in the potential of scavenging superoxide anions and free radicals by capsaicin was observed for the doses of 20, 40, 80 and 100 μM. The exposure of capsaicin not only significantly increased the GSH (max.
Acta biologica Hungarica  •  2018  |  View Paper
Our results further demonstrate that capsaicin treatment not only inhibit the enzymatic activity and expression of SOD, catalase and glutathione peroxidase but also reduce glutathione level.
PloS one  •  2011  |  View Paper
Addition of GSH (2 mM) to microsomal incubations stimulated the metabolism of capsaicin and trapped several reactive electrophilic intermediates as their GSH adducts.
Chemical research in toxicology  •  2003  |  View Paper
CAP pretreatment attenuated ALI … (SOD) and glutathione ( GSH )); downregulate expression of proinflammatory cytokines (interleukin (IL)-6, IL-1β, tumor necrosis factor-α) through the high-mobility group box 1/… pathway; alleviate hepatocyte apoptosis by inhibiting expression of B-cell lymphoma-2-associated X, caspase-3 and cleaved caspase-3.
Clinical immunology  •  2020  |  View Paper
GSH and PON-1 activity increased after capsaicin , phenytoin or capsaicin/phenytoin.
Neurochemical Research  •  2020  |  View Paper
In lung tissue, both MDA and GSH were decreased by capsaicin administration.
Inflammopharmacology  •  2011  |  View Paper