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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Capsaicin
supplement:
Glutathione
Research Papers that Mention the Interaction
“A dose dependent significant increase in the potential of scavenging superoxide anions and free radicals by capsaicin was observed for the doses of 20, 40, 80 and 100 μM. The exposure of capsaicin not only significantly increased the GSH (max.”
Effect of capsaicin on the oxidative stress and dopamine content in the transgenic Drosophila model of Parkinson's disease.“Our results further demonstrate that capsaicin treatment not only inhibit the enzymatic activity and expression of SOD, catalase and glutathione peroxidase but also reduce glutathione level.”
“Addition of GSH (2 mM) to microsomal incubations stimulated the metabolism of capsaicin and trapped several reactive electrophilic intermediates as their GSH adducts.”
“… CAP pretreatment attenuated ALI … (SOD) and glutathione ( GSH )); downregulate expression of proinflammatory cytokines (interleukin (IL)-6, IL-1β, tumor necrosis factor-α) through the high-mobility group box 1/… pathway; alleviate hepatocyte apoptosis by inhibiting expression of B-cell lymphoma-2-associated X, caspase-3 and cleaved caspase-3.”
Capsaicin alleviates acetaminophen-induced acute liver injury in mice.“ GSH and PON-1 activity increased after capsaicin , phenytoin or capsaicin/phenytoin.”
“In lung tissue, both MDA and GSH were decreased by capsaicin administration.”
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