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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Capsaicin
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“The stimulatory effect of capsaicin on GABA release was prevented when AMPA/KA or NMDA, but not AMPA receptors were blocked.”
Presynaptic ionotropic glutamate receptors modulate GABA release in the mouse dorsal motor nucleus of the vagus“Following perineural treatment of capsaicin for 30 min, both the GABA-immunostaining density and the number of GABA immunoreactive neurons were reduced significantly in the ipsilateral laminae I-II at L5 through L7.”
“ GABA activation current significantly increased in the DRG cells of the capsaicin group, which could be reversed by bumetanide.”
Improving NKCC1 Function Increases the Excitability of DRG Neurons Exacerbating Pain Induced After TRPV1 Activation of Primary Sensory Neurons
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