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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Capsaicin and EMLA

supplement:

Capsaicin

drug:

EMLA

Research Papers that Mention the Interaction

In conclusion, pre-treatment with EMLA significantly reduced the burning sensation from capsaicin and attenuated heat hyperalgesia during treatment.
Acta dermato-venereologica  •  1999  |  View Paper
Average and peak pain ratings were significantly lower at the EMLA site during the first 15-30 min of capsaicin treatment.
EMLA fails to produce a long lasting attenuation of the pain induced by topical application of 1% capsaicin.
These results argue against the use of EMLA to block pain to topical capsaicin during the treatment of neurogenic pain.
Pain  •  1999  |  View Paper
CONCLUSION:We observed that the combination of capsaicin and EMLA in a low concentration is as effective in managing venous cannulation as when applied as an individual drug alone.
Anesthesia and analgesia  •  2013  |  View Paper
Yosipovitch et al. (1) showed that EMLA significantly reduces the burning sensation from capsaicin , whereas Fuchs et al. (2) argue against the use of EMLA to block pain due to topical capsaicin.
Acta anaesthesiologica Scandinavica  •  2001  |  View Paper
This study also suggests the existence of a synergistic effect of capsaicin and EMLA on the process of neurogenic inflammation.
The journal of pain  •  2021  |  View Paper