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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Capsaicin and Dihydroergotamine

Research Papers that Mention the Interaction

Intrathecal dihydroergotamine (10, 31 and 100μg) inhibited the vasodilatation to capsaicin , but not that to α-CGRP or acetylcholine.
Thus, intrathecal (C(1)-C(3)) dihydroergotamine seems to inhibit the external carotid vasodilatation to capsaicin by spinal activation of serotonin 5-HT(1B/1D) (probably 5-HT(1B)) receptors and α(2) (probably α(2A/2C))-adrenoceptors.
European journal of pharmacology  •  2012  |  View Paper