Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Capsaicin and Dihydroergotamine

Research Papers that Mention the Interaction

Intrathecal dihydroergotamine (10, 31 and 100μg) inhibited the vasodilatation to capsaicin , but not that to α-CGRP or acetylcholine.
Thus, intrathecal (C(1)-C(3)) dihydroergotamine seems to inhibit the external carotid vasodilatation to capsaicin by spinal activation of serotonin 5-HT(1B/1D) (probably 5-HT(1B)) receptors and α(2) (probably α(2A/2C))-adrenoceptors.
European journal of pharmacology  •  2012  |  View Paper