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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Capsaicin and Collagenases

supplement:

Capsaicin

Research Papers that Mention the Interaction

Capsaicin , a homovanillic acid derivative that acts as a releaser of SP from primary afferent neurons, caused a strong stimulation of collagenase production and release at 10(-8) and 10(-6) M (about 7 times the amount of the control).
Scandinavian journal of rheumatology  •  1991  |  View Paper
Capsaicin at both doses induced an increase in the synthesis of collagenase and at the lower concentration (10(-8) mol/l) only of prostaglandins.
The mechanisms by which capsaicin stimulates DNA synthesis and production of collagenase and prostaglandin E2, in a manner dependent on dose, remain to be determined.
Annals of the rheumatic diseases  •  1990  |  View Paper
Curcumin and capsaicin also inhibited the secretion of collagenase , elastase, and hyaluronidase to the maximum extent of 57, 61, 66%, and 46, 69, 67%, respectively.
Lipids  •  1997  |  View Paper