supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Capsaicin
drug:
Ciprofloxacin
Research Papers that Mention the Interaction
“Furthermore, capsaicin also extended the post-antibiotic effect of ciprofloxacin by 1.1 h at MIC concentration.”
“RESULTS Ca saicin si gnificantly reduced the MIC of cip rofloxacin fo r S. aureus SA-1199 and SA-1199B.”
“There was a decrease in mutation prevention concentration of ciprofloxacin when combined with capsaicin.”
Capsaicin, a novel inhibitor of the NorA efflux pump, reduces the intracellular invasion of Staphylococcus aureus.“Considering that 0.01% or 0.1% capsaicin are unlikely to upset the gastrointestinal tract, … if a similar effect occurs in man, and to evaluate if the addition of capsaicin can be used as a method to increase the … rate, a key variable to improve clinical efficacy of ciprofloxacin.”
“The results revealed that capsaicin increased ciprofloxacin bioavailability by approximately 70% in groups receiving preparations containing capsaicin at a rate of 0.01, 0.1 and 0.5%.”
“… capsaicin … ciprofloxacin (1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, CAS 85721-33-1, Bay q 3939) in rats, … 404-86-4) dissolved in ethanol and mixed with 20 mg/kg of ciprofloxacin were orally administered to groups of 10 rats each.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback