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Last Updated: a year ago

Possible Interaction: Capsaicin and Ciprofloxacin

supplement:

Capsaicin

Research Papers that Mention the Interaction

Furthermore, capsaicin also extended the post-antibiotic effect of ciprofloxacin by 1.1 h at MIC concentration.
RESULTS Ca saicin si gnificantly reduced the MIC of cip rofloxacin fo r S. aureus SA-1199 and SA-1199B.
There was a decrease in mutation prevention concentration of ciprofloxacin when combined with capsaicin.
The Journal of antimicrobial chemotherapy  •  2012  |  View Paper
Considering that 0.01% or 0.1% capsaicin are unlikely to upset the gastrointestinal tract, … if a similar effect occurs in man, and to evaluate if the addition of capsaicin can be used as a method to increase the … rate, a key variable to improve clinical efficacy of ciprofloxacin.
The results revealed that capsaicin increased ciprofloxacin bioavailability by approximately 70% in groups receiving preparations containing capsaicin at a rate of 0.01, 0.1 and 0.5%.
capsaicin … ciprofloxacin (1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, CAS 85721-33-1, Bay q 3939) in rats, … 404-86-4) dissolved in ethanol and mixed with 20 mg/kg of ciprofloxacin were orally administered to groups of 10 rats each.
Arzneimittel-Forschung  •  2007  |  View Paper