Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Capsaicin and Cholecystokinin

supplement:

Capsaicin

Research Papers that Mention the Interaction

Because it has been reported that systemic or perivagal capsaicin pretreatment abolishes the effects of CCK , the aim of the present work was to investigate the response of cNTS neurons to CCK-8s in vagally deafferented rats.
American journal of physiology. Regulatory, integrative and comparative physiology  •  2007  |  View Paper
Capsaicin treatment destroys vagal afferent C fibers and markedly attenuates reduction of food intake and induction of hindbrain Fos expression by CCK.
When CCK was administered during gastric distension, it significantly enhanced NTS Fos expression in response to distension in Cap rats.
American journal of physiology. Regulatory, integrative and comparative physiology  •  2005  |  View Paper
These results suggest that capsaicin influence neuropeptides such as orexigenic NPY and anorexigenic CCK related to control food intake.
Journal of nutritional science and vitaminology  •  2004  |  View Paper
It was expected that only capsaicin-sensitive C-type neurons would respond to CCK, because most vagally mediated actions of CCK are blocked by capsaicin treatment.
American journal of physiology. Gastrointestinal and liver physiology  •  2003  |  View Paper
Perivagal application of capsaicin increased plasma CCK levels and significantly increased pancreatic wet weight compared with those in the control rats.
American journal of physiology. Gastrointestinal and liver physiology  •  2003  |  View Paper
The pretreatment with L-NNA to inhibit NO-synthase activity attenuated significantly the protective and hyperemic effects of CCK but not those of leptin while capsaicin denervation counteracted leptin-induced protection and rise in the GBF but attenuated significantly those of CCK.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society  •  2001  |  View Paper
In conscious rats, perivagal application of capsaicin abolished the pancreatic response evoked by physiological doses of CCK and intraduodenal administration of maltose or hypertonic saline, confirming the physiological relevance of the observations in anaesthetized rats.
The Journal of physiology  •  1996  |  View Paper
The hyperemia, but not the protection, afforded by CCK and pentagastrin was reduced after sensory nerve deactivation with capsaicin.
Scandinavian journal of gastroenterology  •  1995  |  View Paper
Treatment of neonatal rats with capsaicin attenuated the satiety effect of injected CCK in adult life.
Brain Research  •  1992  |  View Paper
Capsaicin treatment attenuates suppression of food intake induced by systemic administration of cholecystokinin (CCK) but not by gastric distension.
The American journal of physiology  •  1989  |  View Paper
Show More