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Last Updated: a year ago

Possible Interaction: Capsaicin and Captopril



Research Papers that Mention the Interaction

However, captopril significantly shifted the dose-response curve to capsaicin inhalation.
The Lancet  •  1987  |  View Paper
In normal subjects, an oral dose of captopril (25 mg) causes a significant shift in the dose-response curve to capsaicin inhalation, but not that to distilled water or citric acid.
Journal of cardiovascular pharmacology  •  1989  |  View Paper
Pretreatment of guinea pigs with capsaicin (100 μg/kg) slightly suppressed the bronchoconstriction by BK alone and almost all of the enhancement of BK-induced bronchoconstriction by captopril was suppressed.
Inflammation Research  •  2005  |  View Paper
After pretreatment with phosphoramidon and captopril, capsaicin increased the Evans blue leakage above the baseline in the trachea, but not in the lung.
British journal of pharmacology  •  1999  |  View Paper
These responses were inhibited by capsaicin pretreatment and the neurokinin type 1 antagonist N-acetyltrifluoromethyl tryptophan benzyl ester and were potentiated by the peptidase inhibitors phosphoramidon and captopril , suggesting that these responses were mediated by tachykinin.
Journal of applied physiology  •  1999  |  View Paper
After pretreatment with the NK‐1 receptor antagonist CP 99994 (10−7 M), substance P (10−8 M; P < 0.001) and capsaicin (10−6 M: P < 0.01)‐induced relaxations were reduced.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society  •  1998  |  View Paper
A pretreatment with capsaicin statistically (P < 0.05) enhanced EFS-induced contraction in all tested preparations respect to tissues incubated with atropine, thiorphan and captopril.
Pulmonary pharmacology & therapeutics  •  1997  |  View Paper
5 Both low dose SP (1 nmol) and capsaicin (1 nmol)‐induced hyperalgesia were potentiated by the kininase II inhibitor captopril (100 μg).
British journal of pharmacology  •  1996  |  View Paper
3 Captopril (8–1000 μg kg−1) enhanced dose‐dependently the BC induced by capsaicin.
British journal of pharmacology  •  1990  |  View Paper
Following a comparable experimental protocol, Long-Evans rats treated neonatally with capsaicin showed a more marked hypotensive response to captopril administration than did vehicle-injected animals.
Neuroscience Letters  •  1986  |  View Paper