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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Capsaicin and Capsaicinoid

supplement:

Capsaicin

supplement:

Capsaicinoid

Research Papers that Mention the Interaction

The incubation with the lowest concentrations (0.1 and 1 μM) of capsaicinoids (natural extract, capsaicin, dihydrocapsaicin) showed a stimulatory effect on caffeine metabolism, which was further enhanced with capsaicin.
European Journal of Drug Metabolism and Pharmacokinetics  •  2010  |  View Paper
Assays of capsaicin biosynthetic precursors suggest that the lateral chain of capsaicinoids has more inhibitory activity than the phenolic part.
Plant biology  •  2014  |  View Paper
Furthermore, the differential expression levels of Kas, Pal and pAmt, which are associated with the capsaicinoid biosynthetic pathway, were also suppressed in the placenta by capsaicin treatment.
These results support that capsaicin , a feedback inhibitor, plays a pivotal role in regulating gene expression which is involved in the biosynthesis of capsaicinoids.
Molecules and cells  •  2009  |  View Paper