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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“At the time of injection of capsaicin , there is an increase in release of aspartate (191+/-21%) and glutamate (194+/-14%).”
“KT5823, H89, or artificial cerebrospinal fluid (ACSF; control) were administered after injection of capsaicin to reduce the increased release of aspartate and glutamate.”
Increased spinal release of excitatory amino acids following intradermal injection of capsaicin is reduced by a protein kinase G inhibitor“ Capsaicin (1 microM) stimulated the release of aspartate and glutamate, as reported for substance P, in control slices but this effect was not as apparent in tissues from capsaicin-treated rats.”
“In capsaicin-treated rats, the evoked release of aspartate , glutamate and substance P but not GABA, were significantly lower.”
“An almost equal increase in serotonin and a less pronounced, but still significant, increase in aspartate accompanied contralateral capsaicin injection.”
“Extracellular concentrations of aspartate , glutamate and serotonin increased significantly following capsaicin injection into the ipsilateral limb.”
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