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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Capsaicin
supplement:
Allyl Isothiocyanate
Research Papers that Mention the Interaction
“… capsaicin was … ( AITC : 2.42 [2.37–2.48] vs 2.72 [2.66–2.78] mM, p = 0.001; capsaicin: 1.87 [1.75–1.….70] μM, p = 0.001) and was higher in females than in males for both healthy subjects and patients (all p < 0.05).”
Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough“In anesthetized, spontaneously breathing rats, the reflex-mediated apneic response to intravenous injection of a combined dose of allyl isothiocyanate (AITC, a TRPA1 activator) and capsaicin (Cap, a TRPV1 activator) was ∼202% greater than the mathematical sum of the responses to AITC and Cap when they were administered individually.”
A synergistic effect of simultaneous TRPA1 and TRPV1 activations on vagal pulmonary C-fiber afferents.“Moreover, contractions induced by AITC generate cross-desensitization with icilin and capsaicin.”
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