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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Capric Acid
drug:
Propylene Glycol
Research Papers that Mention the Interaction
“ Capric acid and dodecylamine, but not lauric acid or neodecanoic acid, increased the skin permeation rate of PG , suggesting that enhanced solvent penetration could also be involved as a mechanism for increased skin permeation of the drug.”
Contributions of Drug Solubilization, Partitioning, Barrier Disruption, and Solvent Permeation to the Enhancement of Skin Permeation of Various Compounds with Fatty Acids and Amines“The highest maximum permeation flux was obtained with 3% capric acid in PG followed by 6% capric acid and 3% oleic acid from solution formulations; the enhancement factor by the addition of 3% capric acid to PG was 20.5 compared to PG alone.”
The effects of fatty acids in propylene glycol on the percutaneous absorption of alendronate across the excised hairless mouse skin.
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