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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Capric Acid
drug:
Perampanel
Research Papers that Mention the Interaction
“Because each compound has been proposed to act through a distinct AMPA receptor binding site, we predicted that perampanel and decanoic acid would act synergistically against AMPA receptors and, consequently, seizures.”
“Here, we show a synergistic interaction between perampanel and decanoic acid in direct AMPA receptor inhibition, in an ex vivo model of seizure activity, and against seizure‐induced activity in human brain slices.”
“These data support a potential role for combination treatment using perampanel and dietary decanoic acid to provide enhanced seizure control.”
Perampanel and decanoic acid show synergistic action against AMPA receptors and seizures
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