Possible Interaction: Cannabinoids and Tetrahydrocannabinol (THC)

“However, the "high" effect of THC in cannabis and cannabinoid may limit the clinical use, particularly, the study on the therapeutic potential of THC alone is more limited.”

“In addition, we found that the cannabinoids CBD and THC dose-dependently (at 0.1–5 μM) suppressed the production and secretion of this cytokine.”

“Scientific evidence is presented for non‐cannabinoid plant components as putative antidotes to intoxicating effects of THC that could increase its therapeutic index.”

“Moreover, products that exceed legal THC levels may jeopardize a consumer’s employment status (i.e. failed “drug test”), while those adulterated with synthetic cannabinoids may subject them to serious adverse health effects.”

“However, because of the various side effects of cannabinoids , especially △9-tetrahydrocannabinol (THC), many countries regulate upper limits for THC in products, which creates the need for analytical techniques capable of measuring THC, cannabidiol (CBD), and cannabinol (CBN) levels in commercial hemp seeds and hempseed oil.”

“BACKGROUND As long-term use of medicinal and recreational cannabis becomes more common and concentrations of delta-9-tetrahydrocannabinol (THC) in cannabis increase, it is timely to identify strategies to counteract the cognitive effects of cannabinoids.”

“There was a trend for greater difference in agitation with synthetic cannabinoids over tetrahydrocannabinol (χ²₁ = 3.05, P = .08).”

“The combination of other cannabinoids together with noncannabinoid components could enhance the beneficial effects of THC and could reduce undesirable side effects.”

“The synthetic cannabinoids (SCs) represent the most recent advent of the new psychotropic substances (NPS) and has become popularly known to mitigate the effects of the Δ(9)-THC.”

“In some cases THC must be introduced to remove long-term blocks mediated by the cannabinoid system.”