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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cannabinoids and Selective Serotonin Reuptake Inhibitors

Research Papers that Mention the Interaction

Given the significant SSRI –cannabinoid interactions, clinicians should discuss THC and CBD use in youth prescribed SSRIs and be aware of the impact of initiating, stopping, or decreasing cannabinoid use as this may significantly affect es/citalopram and sertraline exposure.
We sought to (1) review clinically relevant pharmacokinetic (PK) and pharmacodynamic (PD) interactions between cannabinoids and selected SSRIs, (2) use PK models to examine … on SSRI exposure (area under curve (AUC)) and maximum concentration (CMAX) in adolescents, and (3) examine the frequency of adverse events reported when SSRIs … cannabinoids ….
Journal of personalized medicine  •  2021  |  View Paper