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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cannabinoids
supplement:
Progesterone
Research Papers that Mention the Interaction
“Ovarian steroids, estrogen and progesterone , influence the sensitivity of certain neural processes to cannabinoid treatment by modulation of brain dopaminergic activity.”
Progesterone receptor and dopamine receptors are required in Delta 9-tetrahydrocannabinol modulation of sexual receptivity in female rats.“Abstract Various cannabinoids inhibited both basal and FSH-stimulated progesterone synthesis by pig and rat granulosa cells in vitro in a dose- (0.09 – 16 μM) and time- (4 – 24 h) dependent manner.”
“ Progesterone production by isolated rat luteal cells was inhibited by exposure to various cannabinoids in concentrations from 3.0--16.0 microM. The available evidence points to the cleavage of cholesterol esters as the site of inhibition.”
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