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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cannabinoids
Research Papers that Mention the Interaction
“Behavioral experiments in rodents and in vitro studies investigating the combined effect of MDMA and cannabinoid agents demonstrate modulator effects of acute co-administration on measures like body temperature, conditioned reinforcement, and presumed neurotoxicity.”
MDMA & cannabis: a mini-review of cognitive, behavioral, and neurobiological effects of co-consumption.“The results suggest that pre-exposure to cannabinoids strengthens the properties of MDMA and favors reinstatement of the craving for the drug, which endorses the gateway hypothesis.”
Effect of adolescent exposure to WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference“Finally, the potential neuroprotective action of cannabinoids is not supported by our data; on the contrary, they are evidence of the potential neurotoxic effect of said drugs when administered with MDMA.”
“On the other hand, WIN 55212-2-induced CPP was reinstated by priming injections … WIN did not reinstate the MDMA-induced CPP.ConclusionsThese results confirm that the cannabinoid system plays a role … effects of MDMA and highlights the risks that sporadic drug … pose in terms of relapse to dependence.”
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