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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cannabinoids and Kynurenic Acid

Research Papers that Mention the Interaction

Recently, we demonstrated that enhancing endogenous levels of kynurenic acid (KYNA, a neuroinhibitory product of tryptophan metabolism) counteracts the rewarding effects of cannabinoids by acting as a negative allosteric modulator of α7 nicotinic receptors (α7nAChRs).
Neuropsychopharmacology  •  2017  |  View Paper