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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cannabinoids
drug:
Kynurenic Acid
Research Papers that Mention the Interaction
“Recently, we demonstrated that enhancing endogenous levels of kynurenic acid (KYNA, a neuroinhibitory product of tryptophan metabolism) counteracts the rewarding effects of cannabinoids by acting as a negative allosteric modulator of α7 nicotinic receptors (α7nAChRs).”
Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys
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