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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Cannabinoids
drug:
Ketoconazole
Research Papers that Mention the Interaction
“The 11-hydroxylation of three cannabinoids by the microsomes was markedly inhibited by sulfaphenazole, a selective inhibitor of CYP2C enzymes, … the hydroxylations at the 7alpha-(Delta(8)-THC), 8beta-(Delta(9)-THC) and 8-positions (CBN) of the corresponding cannabinoids were highly … by ketoconazole , a selective inhibitor … CYP3A enzymes.”
Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes.
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