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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cannabidiol
drug:
Warfarin
Research Papers that Mention the Interaction
“Additional studies should be performed to clarify the interaction potential of cannabidiol and warfarin.”
“INR should be monitored frequently in patients taking warfarin who begin to take FDA-approved cannabidiol.”
“PURPOSE A case of a possible interaction between cannabidiol and warfarin is presented along with a brief overview of cytochrome enzymes involved in these drugs' metabolism.”
Warfarin dose adjustment required after cannabidiol initiation and titration.“The other case study reported of a patient who initiated treatment with a liquid formulation of cannabidiol for the management of epilepsy, ultimately necessitating a 30% reduction in warfarin dose to maintain therapeutic INR values.”
“Highlights • An interaction between warfarin and cannabidiol is described• The mechanisms of cannabidiol and warfarin metabolism are reviewed• Mechanism of the interaction is proposed• INR should be monitored in patients when cannabinoids are introduced”
An interaction between warfarin and cannabidiol, a case report
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