Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Cannabidiol and Warfarin

supplement:

Cannabidiol

Research Papers that Mention the Interaction

Additional studies should be performed to clarify the interaction potential of cannabidiol and warfarin.
INR should be monitored frequently in patients taking warfarin who begin to take FDA-approved cannabidiol.
PURPOSE A case of a possible interaction between cannabidiol and warfarin is presented along with a brief overview of cytochrome enzymes involved in these drugs' metabolism.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists  •  2020  |  View Paper
The other case study reported of a patient who initiated treatment with a liquid formulation of cannabidiol for the management of epilepsy, ultimately necessitating a 30% reduction in warfarin dose to maintain therapeutic INR values.
Basic & clinical pharmacology & toxicology  •  2019  |  View Paper
Highlights • An interaction between warfarin and cannabidiol is described• The mechanisms of cannabidiol and warfarin metabolism are reviewed• Mechanism of the interaction is proposed• INR should be monitored in patients when cannabinoids are introduced
Epilepsy & Behavior Case Reports  •  2018  |  View Paper