Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Cannabidiol and Temozolomide

supplement:

Cannabidiol

Research Papers that Mention the Interaction

Previous observations from our group demonstrated that … administration of THC (or of THC + CBD at a 1:1 ratio, a mixture that resembles the … of the cannabinoid‐based medicine Sativex®) in combination with Temozolomide , the benchmark agent for the treatment of GBM, synergistically reduces the growth of glioma xenografts.
Biochemical pharmacology  •  2018  |  View Paper
We also found that the administration of THC (or of THC + CBD at a 1:1 ratio) in combination with temozolomide (TMZ), the benchmark agent for the treatment of GBM, synergistically reduces the growth of glioma xenografts.
Biochemical pharmacology  •  2018  |  View Paper
Lastly, CBD and temozolomide combination therapy in patient-derived neurosphere cultures and mouse orthotopic models showed significant synergistic effect in both controlling tumor size and improving survival.
Autophagy  •  2021  |  View Paper