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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cannabidiol and Tamoxifen

supplement:

Cannabidiol

Research Papers that Mention the Interaction

In the present study we have demonstrated a synergistic cytotoxic effect of TAM and CBD against T-ALL cells.
International journal of molecular sciences  •  2021  |  View Paper
It was postulated that CBD may diminish tamoxifen metabolism by CYP3A4 and 2D6 to form active metabolite endoxifen, which exerts the anticancer benefits.
Patients receiving CBD and interacting chemotherapeutic drugs, such as tamoxifen , require monitoring to identify possible subtherapeutic response to treatment.
Journal of pharmacy practice  •  2020  |  View Paper