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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cannabidiol
drug:
Serotonin Agents
Research Papers that Mention the Interaction
“In particular, due to its complex pharmacological properties, it seems that CBD may interact with several neurotransmitter systems, including the serotonergic , glutamatergic, and endocannabinoid ones, and may induce neurobiological changes associated with depression.”
Cannabidiol for Mood Disorders: A Call for More Research“In conclusion, our findings indicate that CBD could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate cortical signalling through a 5-HT1A receptor-dependent mechanism.”
Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors“ CBD has been reported to functionally interact with both the mesolimbic dopamine (DA) and serotonergic (5-HT) receptor systems.”
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