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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cannabidiol and Phenytoin

supplement:

Cannabidiol

Research Papers that Mention the Interaction

Relatively large doses of Δ 9 -THC, on the other hand, and all doses of CBD depressed the reflex, as did PHT ; such depression may account, at least partially, for the anticonvulsant effects of the cannabinoids.
Neuropharmacology  •  1981  |  View Paper
The anticonvulsant potency of phenytoin was significantly increased when combined with phenobarbital, CBD and phenobarbital plus CBD.
The Journal of pharmacology and experimental therapeutics  •  1977  |  View Paper