Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Cannabidiol and Phenytoin

supplement:

Cannabidiol

Research Papers that Mention the Interaction

Relatively large doses of Δ 9 -THC, on the other hand, and all doses of CBD depressed the reflex, as did PHT ; such depression may account, at least partially, for the anticonvulsant effects of the cannabinoids.
Neuropharmacology  •  1981  |  View Paper
The anticonvulsant potency of phenytoin was significantly increased when combined with phenobarbital, CBD and phenobarbital plus CBD.
The Journal of pharmacology and experimental therapeutics  •  1977  |  View Paper