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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Cannabidiol and Paclitaxel

supplement:

Cannabidiol

Research Papers that Mention the Interaction

While PTX conducted to a 1.5-fold tumor growth inhibition, its combination with both CBD in solution (daily administered) and 10-Mps (single administration) showed a 2-fold decrease.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V  •  2020  |  View Paper
CBDsol , previously administered at suboptimal concentrations (cell death <10%), enhanced the PTX and DOX effect in both breast cancer cells.
The co-administration of CBDsol and PTX or DOX showed a synergistic effect.
International journal of pharmaceutics  •  2019  |  View Paper
Paclitaxel produced allodynia that was largely dose independent and more robust in female mice, and this effect was prevented by treatment with cannabidiol.
Anesthesia and analgesia  •  2011  |  View Paper