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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Cannabidiol
drug:
Norfloxacin
Research Papers that Mention the Interaction
“HighlightsCBD induces antidepressant‐like effects in FST.Subeffective doses of CBD with FLX , but not DES, reduce the immobility time in the FST.Serotonin, but not noradrenaline, reduction abrogates the CBD effects in the FST.”
“Ineffective doses of CBD (7 mg/kg), when co‐administered with ineffective doses of FLX (5 mg/kg) or DES (2.5 mg/kg) resulted in significant antidepressant‐like effects, thus implicating synergistic and/or additive mechanisms.”
Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels“A similar effect was found when subeffective doses of CBD (15 mg/kg) and FLX (3 mg/kg) were administered together.”
“As found previously, CBD (30 mg/kg) and the positive control fluoxetine ( FLX ; 10 mg/kg) decreased burying behavior without changing general exploratory activity.”
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