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Last Updated: a year ago

Possible Interaction: Cannabidiol and Midazolam

supplement:

Cannabidiol

Research Papers that Mention the Interaction

In this current commentary, we will direct separate attention toward the four-drug combination of midazolam (MDZ) with CBD used for specific contexts of motor-sparing perineural analgesia.
Pain medicine  •  2015  |  View Paper
In addition, mice pretreated with cannabidiol (150 mg/kg) had a modest reduction in seizure severity after midazolam treatment compared to vehicle-pretreated.
These findings of improved outcome with cannabidiol administration in a severe seizure model of soman exposure provide additional pre-clinical support for the benefits of cannabidiol against exposure to seizure-inducing chemical agents and suggest cannabidiol may augment the anti-seizure effects of midazolam.
Neurotoxicology  •  2020  |  View Paper