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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Cannabidiol
supplement:
Linoleic Acid
Research Papers that Mention the Interaction
“Administration of CBD to cultured human sebocytes and human skin organ culture inhibited the lipogenic actions of various compounds, including arachidonic acid and a combination of linoleic acid and testosterone, and suppressed sebocyte proliferation via the activation of transient receptor potential vanilloid-4 (TRPV4) ion channels.”
Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.“The aim of this study was to test the … that pre-digested lipid formulations (oleic acid, linoleic acid , oleic acid with 2-oleoylglycerol, oleic acid with 2-oleoylglycerol and oleic acid with glycerol) … reduce variability and increase the extent of the intestinal lymphatic transport and oral bioavailability of CBD.”
Natural sesame oil is superior to pre-digested lipid formulations and purified triglycerides in promoting the intestinal lymphatic transport and systemic bioavailability of cannabidiol.
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