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“In vivo exposure of tumor tissues to CBD significantly decreased the activity and content of 5‐lipoxygenase (LOX, by ∼ 40%), and of its end product leukotriene B4 (∼ 25%).”
“As a consequence of reductions in phospholipase A2 and cyclooxygenases activity following UV irradiation, CBD upregulates the level of 2-arachidonoylglycerol and downregulates prostaglandin E2 and leukotriene B4.”