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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cannabidiol and Heroin

supplement:

Cannabidiol

drug:

Heroin

Research Papers that Mention the Interaction

CBD exhibited potent in vitro inhibition toward both heroin and 6-MAM hydrolysis, which may be of potential clinical relevance.
CBD inhibited heroin and 6-MAM hydrolysis in a reversible manner, with IC50s of 14.7 and 12.1 μM, respectively.
Chemico-biological interactions  •  2019  |  View Paper
Among the studies of CBD’s “anti-addiction” potential, a major positive finding reported by Hurd and colleagues [3] was that CBD attenuates cue-induced heroin reinstatement with effects that outlasted treatment by two weeks.
Neuropsychopharmacology  •  2018  |  View Paper
It has been shown that cannabidiol attenuates cue‐induced reinstatement of heroin seeking.
Addiction biology  •  2013  |  View Paper