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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cannabidiol
drug:
Heroin
Research Papers that Mention the Interaction
“ CBD exhibited potent in vitro inhibition toward both heroin and 6-MAM hydrolysis, which may be of potential clinical relevance.”
“ CBD inhibited heroin and 6-MAM hydrolysis in a reversible manner, with IC50s of 14.7 and 12.1 μM, respectively.”
The influence of carboxylesterase 1 polymorphism and cannabidiol on the hepatic metabolism of heroin.“Among the studies of CBD’s “anti-addiction” potential, a major positive finding reported by Hurd and colleagues [3] was that CBD attenuates cue-induced heroin reinstatement with effects that outlasted treatment by two weeks.”
“It has been shown that cannabidiol attenuates cue‐induced reinstatement of heroin seeking.”
Cannabidiol inhibits the reward‐facilitating effect of morphine: involvement of 5‐HT1A receptors in the dorsal raphe nucleus
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