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Last Updated: 4 months ago

Possible Interaction: Cannabidiol and Haloperidol

supplement:

Cannabidiol

Research Papers that Mention the Interaction

Daily CBD administration before each haloperidol injection prevented this effect.
The combination of CBD and haloperidol also increased PGC-1α mRNA expression, a co-activator of PPARγ receptors.
The present study investigated if CBD would attenuate orofacial dyskinesia, oxidative stress and inflammatory changes induced by chronic administration of haloperidol in mice.
Brain, Behavior, and Immunity  •  2018  |  View Paper
To further investigate this latter effect, we tested whether CBD (15-60mg/kg) would attenuate the catalepsy and c-Fos protein expression in the dorsal striatum induced by haloperidol (0.6mg/kg).
Behavioural Brain Research  •  2016  |  View Paper
Conclusions: We confirmed that CBD can ameliorate motor impairments produced by haloperidol.
Our data suggest that CBD can be combined with haloperidol to prevent the emergent of extrapyramidal side effects and long-term movement disorders, such as acute dystonic disorder and TD.
Results: This study found that CBD co-administration with haloperidol attenuated the VCMs and increased motor tone produced by haloperidol.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry  •  2020  |  View Paper