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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cannabidiol
drug:
Dopamine
Research Papers that Mention the Interaction
“Through these multiple-receptor mechanisms, CBD is believed to modulate brain dopamine in response to drugs of abuse, leading to attenuation of drug-taking and drug-seeking behavior.”
Possible Receptor Mechanisms Underlying Cannabidiol Effects on Addictive-like Behaviors in Experimental Animals“Co-administration of dopamine with either CBD or CBDV caused paralysis similar to that of either phytocannabinoid treatment alone.”
Involvement of dopamine receptor in the actions of non-psychoactive phytocannabinoids.“Moreover, experimental evidence has shown that injections of CBD enhance wake-related compounds, such as monoamines ( dopamine , serotonin, epinephrine, and norepinephrine).”
“ CBD has been reported to functionally interact with both the mesolimbic dopamine ( DA ) and serotonergic (5-HT) receptor systems.”
“On the contrary, CBD is already known to modulate brain excitatory glutamate, inhibitory γ-aminobutyric acid (GABA) and dopamine neurotransmission.”
The Transcriptomic Analysis of NSC-34 Motor Neuron-Like Cells Reveals That Cannabigerol Influences Synaptic Pathways: A Comparative Study with Cannabidiol
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