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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cannabidiol and Dopamine

supplement:

Cannabidiol

Research Papers that Mention the Interaction

Through these multiple-receptor mechanisms, CBD is believed to modulate brain dopamine in response to drugs of abuse, leading to attenuation of drug-taking and drug-seeking behavior.
International journal of molecular sciences  •  2020  |  View Paper
Co-administration of dopamine with either CBD or CBDV caused paralysis similar to that of either phytocannabinoid treatment alone.
Biochemical and biophysical research communications  •  2020  |  View Paper
Moreover, experimental evidence has shown that injections of CBD enhance wake-related compounds, such as monoamines ( dopamine , serotonin, epinephrine, and norepinephrine).
Neurochemical Research  •  2018  |  View Paper
CBD has been reported to functionally interact with both the mesolimbic dopamine ( DA ) and serotonergic (5-HT) receptor systems.
Neuropsychopharmacology  •  2016  |  View Paper
On the contrary, CBD is already known to modulate brain excitatory glutamate, inhibitory γ-aminobutyric acid (GABA) and dopamine neurotransmission.
Life  •  2020  |  View Paper