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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cannabidiol and Corticosterone

Research Papers that Mention the Interaction

Both THC (2 mg/ kg) and CBD (30 mg/kg) increased corticosterone levels in rats, but when the two cannabinoids were simultaneously administered, the additive effect did not occur.
Psychopharmacology  •  2011  |  View Paper
Forty-five min after administration, both delta 9-THC (1, 2 and 4 mg/kg) and CBD (10, 30 and 60 mg/kg) induced a dose-dependent increase in corticosterone levels.
Archives internationales de pharmacodynamie et de therapie  •  1984  |  View Paper
CBD (5 mg/kg, ip) pretreatment reversed the THC-induced increase in CORT.
Cannabis and cannabinoid research  •  2020  |  View Paper