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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cannabidiol and Clonazepam

supplement:

Cannabidiol

Research Papers that Mention the Interaction

Additionally, CBD reliably reduced the anticonvulsant potencies of chlordiazepoxide, clonazepam , trimethadione and ethosuximide.
The Journal of pharmacology and experimental therapeutics  •  1977  |  View Paper
Combination of CLZ with CBD significantly reduced seizure duration compared to the vehicle or CLZ alone, but did not affect seizure severity, indicating potential additive actions of CLZ and CBD on the duration of seizures.
Our findings provide preclinical evidence supporting combination therapy of CLZ and CBD for treatment of febrile seizures in DS.
Journal of experimental neurology  •  2021  |  View Paper