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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cannabidiol
drug:
Clonazepam
Research Papers that Mention the Interaction
“Additionally, CBD reliably reduced the anticonvulsant potencies of chlordiazepoxide, clonazepam , trimethadione and ethosuximide.”
Cannabidiol--antiepileptic drug comparisons and interactions in experimentally induced seizures in rats.“Combination of CLZ with CBD significantly reduced seizure duration compared to the vehicle or CLZ alone, but did not affect seizure severity, indicating potential additive actions of CLZ and CBD on the duration of seizures.”
“Our findings provide preclinical evidence supporting combination therapy of CLZ and CBD for treatment of febrile seizures in DS.”
Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome
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