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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Cannabidiol and Calcium Supplement



Research Papers that Mention the Interaction

CBD responses were prevented by removal of bath calcium , ruthenium red, and the TRPA1 antagonist A967079; but not the TRPV1 antagonist SB366791; suggesting an essential role for TRPA1.
Journal of neurophysiology  •  2020  |  View Paper
When tested individually AEA, CBD or NAGly inhibited SOCE.
Biochemical pharmacology  •  2018  |  View Paper
Both THC and cannabidiol inhibited depolarization-dependent uptake of calcium without affecting the resting uptake (Table I).
The Journal of neuroscience : the official journal of the Society for Neuroscience  •  1982  |  View Paper
CBD also increased mitochondrial concentrations of reactive oxygen species (ROS) (160 ± 53 ….8%, 20 µM CBD vs. control, respectively, p < 0.001) and Ca2+ (187 ± 78 vs. 105 ± 10%, 20 µM CBD vs. the control, respectively, p < … was associated with a significantly decreased mitochondrial branch length and increased fission.
Frontiers in Molecular Biosciences  •  2021  |  View Paper
Furthermore, CBD caused a marked increase in ability to generate LTP, an effect that was blocked by calcium store antagonists as well as by a reduction in serotonin tone.
Front. Mol. Neurosci.  •  2018  |  View Paper