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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cannabidiol
Research Papers that Mention the Interaction
“Finally, we provide evidence that the elevated basal level of ER stress in activated HSCs has a role in their susceptibility to the pro-apoptotic effect of CBD.”
Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis“In conclusion, the data suggested that CBD induced ER stress via Ca2+ influx through the TRPV1 receptor, thereby elevating intracellular ROS levels and disrupting protein folding.”
CBD activation of TRPV1 induces oxidative signalling and subsequent ER stress in breast cancer cell lines.“ CBD triggered the expression of HO-1 and other cell stress markers.”
“ Cannabidiol enhanced significantly DR5 expression by ER stress.”
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